Select an upcoming Colon cruise itinerary list below to find a Colon sailing itinerary by destination, line, or ship. Search All Cruises Lindblad Expeditions11/29/20267 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,532$9,946$10,98812/06/20267 Night South American Cruise The Panama Canal, Pearl Islands and Darién Jungleon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,532$9,946$10,98812/13/20267 Night South American Cruise The Panama Canal, Pearl Islands and Darién Jungleon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,532$9,946$10,98812/20/20267 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$8,332$10,909$11,60212/27/20267 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$8,418$11,017$11,71601/03/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,854$10,767$11,88001/10/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,761$10,460$11,55901/13/20278 Night South American Cruise Inland Costa Rica, the Panama Canal and Pearl Islandson the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$6,801$8,327$8,94701/17/20278 Night South American Cruise Inland Costa Rica, the Panama Canal and Pearl Islandson the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$6,801$8,327$8,94701/21/20278 Night South American Cruise Inland Costa Rica, the Panama Canal and Pearl Islandson the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$6,801$8,327$8,94701/29/20277 Night South American Cruise The Panama Canal, Pearl Islands and Darién Jungleon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,761$10,460$11,55902/06/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,761$10,253$11,33102/13/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,682$10,145$11,21602/20/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,689$10,153$11,21602/27/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,611$10,053$11,10203/06/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,611$10,053$11,10203/13/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,611$10,053$11,10203/20/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,611$10,053$11,10211/27/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,532$9,946$10,98812/04/20277 Night South American Cruise Costa Rica and the Panama Canalon the Lindblad Expeditions Natl Geographic Quest departing from Colon, PanamaInteriorOceanviewBalconySuite-$7,532$9,946$10,988Ponant11/21/202610 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$10,930$23,53012/18/202610 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$10,390$16,36012/19/202610 Night South American Cruiseon the Ponant Le Laperouse departing from Colon, PanamaInteriorOceanviewBalconySuite--$9,850$15,50001/14/202710 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite---$28,61001/15/20277 Night South American Cruiseon the Ponant Le Laperouse departing from Colon, PanamaInteriorOceanviewBalconySuite--$6,890$10,87002/26/20277 Night South American Cruiseon the Ponant Le Laperouse departing from Colon, PanamaInteriorOceanviewBalconySuite--$6,860$10,27003/12/202710 Night South American Cruiseon the Ponant Le Laperouse departing from Colon, PanamaInteriorOceanviewBalconySuite---$15,72004/08/202710 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$7,220$10,64011/28/202710 Night South American Cruiseon the Ponant Le Bellot departing from Colon, PanamaInteriorOceanviewBalconySuite--$10,150$15,98012/02/202710 Night South American Cruiseon the Ponant Le Bougainville departing from Colon, PanamaInteriorOceanviewBalconySuite--$7,600$13,330Royal Caribbean International11/14/202610 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,036$1,990--12/19/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,689$3,911--12/26/20267 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$2,314$2,426$2,933-01/02/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$789$929$1,509$1,64801/09/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,176$1,316$1,579-01/16/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite-$889$1,628$1,66401/23/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$928$1,002-$1,78801/30/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$579$749$1,935$1,71902/06/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,460$1,680$1,830$1,85802/13/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$846$846$1,489$1,73902/20/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$1,336$1,456$1,932$1,58902/27/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$896$906$1,329$1,38903/06/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$835$844$1,479$1,18803/13/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$729$746$1,228$1,81803/20/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$780$789$1,489$1,53803/27/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$796$906$1,637$1,82104/03/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$780$1,032$1,459$1,47904/10/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$798$869$2,838$1,89904/17/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$645$987$2,068$1,74812/04/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$806$926$1,379$1,43812/11/20277 Night Southern Caribbean Cruiseon the Royal Caribbean International Grandeur of the Seas departing from Colon, PanamaInteriorOceanviewBalconySuite$876$865$1,449$1,309Windstar Cruises12/05/20267 Night Central America & Panama Canal Cruiseon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuite-$3,279--12/19/20267 Night Central America & Panama Canal Cruiseon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuite-$3,314--01/02/20277 Night Central America & Panama Canal Cruiseon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuite-$3,279--01/05/20277 Night Central America & Panama Canal Cruiseon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuite-$2,444$3,424-01/19/20277 Night Central America & Panama Canal Cruiseon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuite-$2,724$4,999$6,36401/19/20277 Night Central America & Panama Canal Cruise Costa Rica & Panama Canalon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/31/20278 Night Central America & Panama Canal Cruise Costa Rica & Panama Canalon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability01/31/20278 Night Central America & Panama Canal Cruiseon the Windstar Cruises Wind Star departing from Colon, PanamaInteriorOceanviewBalconySuite-$3,756--02/02/20277 Night Central America & Panama Canal Cruiseon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuite-$2,549-$9,86402/02/20277 Night Central America & Panama Canal Cruise Lima Machu Picchu Pre Cruise Tour to Panamaon the Windstar Cruises 3tar Legend departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/06/20277 Night Central America & Panama Canal Cruise Costa Rica & Panama Canalon the Windstar Cruises Star Pride departing from Colon, PanamaInteriorOceanviewBalconySuiteContact cruise line for pricing & availability12/06/20277 Night Central America & Panama Canal Cruiseon the Windstar Cruises Star Pride departing from Colon, PanamaInteriorOceanviewBalconySuite-$3,319$4,614$6,749