7820 Commerce DriveFlorence, KY 41042 Phone: +1 859-980-1380Fax: +1 859-980-1385Toll Free: +800-4-MOTEL6 Hotel Website Classification 4 Moderate First Class Commission Rooms Rates 8% 48 $47-$47 (USD) Hoteliers! Is your information accurate? Update Here Motel 6 Florence Location & Neighborhood I-71N/I-75N exit 181 - 3.700 MI from Cincinnati/N KY airport.