30725 Overseas HwyBig Pine Key, FL 33043 Phone: +1 305-872-9090Fax: +1 305-872-9191Toll Free: +888-872-9191 Hotel E-mailHotel Website Commission Rooms Rates - 32 - Hoteliers! Is your information accurate? Update Here Big Pine Motel Location & Neighborhood On US Hwy 1, Florida Keys - between Key West & Marathon. 150 MI from MiamiHotel Location: Beach