13050 Clemson BlvdSeneca, SC 29678 Phone: +1 864-280-8800Fax: +1 864-280-8801Toll Free: +844-Tru-You8 Hotel Website Classification 3 Superior Tourist Class Commission Rooms Rates - 98 - Hoteliers! Is your information accurate? Update Here Tru by Hilton Seneca Clemson Location & Neighborhood 48 MI, 1 hr from Greenville/Sprtanbrg airport.