221 Britain StSantee, SC 29142 Phone: +1 803-854-4104Fax: +1 803-854-4305Toll Free: +877-424-6423 Hotel E-mailHotel Website Classification 5 Limited Service First Class Commission Rooms Rates 10% 61 $123-$123 (USD) Hoteliers! Is your information accurate? Update Here Comfort Inn & Suites Santee, SC Location & Neighborhood 60 MI from Charleston Intl airport.Hotel Location: Convention Center, Highway, Lake