831 S Irby StFlorence, SC 29501 Phone: +1 843-662-9421Fax: +1 843-665-5315Toll Free: +800-4-MOTEL6 Hotel Website Classification 2 Tourist Class Commission Rooms Rates 8% 106 - Hoteliers! Is your information accurate? Update Here Motel 6 Florence Historic Downtown Location & Neighborhood US 52 & 301 S - 3 MI, 10 min from Florence airport. 70 MI from Myrtle BeachNearest Cross Street: Cherokee & Irby