3080 South SR 157Edwardsville, IL 62025 Phone: +1 618-656-4900Fax: +1 618-656-0998Toll Free: +877-424-6423 Hotel E-mailHotel Website Classification 3 Superior Tourist Class Commission Rooms Rates 10% 74 - Hoteliers! Is your information accurate? Update Here Comfort Inn Edwardsville Location & Neighborhood Downtown - 20 MI, 30 min from St Louis/Lambert airport. St Louis