Cayo Largo del SurCayo Largo, Cuba Phone: +53 45-248260Fax: +53 45-248265 Hotel Website Classification 7 Superior First Class Commission Rooms Rates 10% 296 - Hoteliers! Is your information accurate? Update Here Memories Cayo Largo Location & Neighborhood In Cayo Largo, a key off the southern coast of Cuba - 0.300 MI from Vilo Acuna Intl airport.Hotel Location: Airport, Beach