3691 St Matthews RdOrangeburg, SC 29118 Phone: +1 803-531-2590Toll Free: +800-733-7663 Hotel E-mailHotel Website Classification 3 Superior Tourist Class Commission Rooms Rates 10% 75 $65-$95 (USD) Hoteliers! Is your information accurate? Update Here Red Roof Inn Orangeburg Location & Neighborhood Located 42.2 miles of Downtown Columbia, off of Hwy 601 - 42 MI, 45 min from Columbia Metro airport. 40 MI from ColumbiaNearest Cross Street: Hwy 601 & I-26Hotel Location: Highway